In appropriate doses, nicotinamide is generally considered safe with few side effects. Usually, supplements or skincare products are used and applied twice a day, once in the morning and again in the evening.
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When taken orally, nicotinamide is generally well-tolerated as large amounts are passed through urine. Its advised that adults should not have doses greater than 35mg per day.
When this dosage is exceeded, minor side effects can include:
- Upset stomach
- Gas
- Dizziness
- Rash or itching
People with pre-existing skin allergies may experience a reaction that could cause redness, itching, or tingling of the skin.
There is a low risk of side effects with nicotinamide supplements, however, you can reduce the risk of such reactions by following these steps before applying products containing nicotinamide:
- Apply a small amount, around the size of a pound coin to your forearm
- Wait 24 hours
- If you experience redness, itching or swelling then wash the area and do not continue to use.
- If you don’t have any side effects, then you should be fine to apply elsewhere.
If you have any concerns about using nicotinamide you should speak to a dermatologist or healthcare professional before application.
Summary
- Nicotinamide is generally well tolerated when doses are kept at 35mg or lower per day.
- Exceeding this dosage can have minor side effects such as an upset stomach, dizziness or redness.
- If you are susceptible to skin allergies should follow precautions or discuss with a dermatologist or skin professional.